1 (wiktionary) 2 (it.wikipedia) 3 (en.wikipedia) 4 (glosbe)

Verbs Nouns Adjectives/Adverbs Pronouns Prepositions Conjunctions
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have a screw loose {v} (to be insane or irrational) lax {adj} (loose; not tight or taut) loose {adj} (not fixed tightly) loose {v} (to make less tight) loosen {v} (to make less tight) one brick short of a full load {adj} (not mentally sound; insane) popup blocker {n} (a piece of software) quantitative easing {n} (monetary policy where the central bank creates money electronically) relax {v} (to become less severe or tense) relax {v} (to become loose) relax {v} (to become more lenient) relax {v} (to make something less severe or tense) relax {v} (to make something loose) relax {v} (to make something (such as codes and regulations) more lenient) sidelock {n} (sidelock)

Just take it easy .	Prenditela comoda.
It was a casual meeting .	È stato un incontro casuale.
These shoes are a little loose .	Queste scarpe sono un po' larghe.
He took it in his stride .	L'ha preso con calma.