effect, result 证件~ credentials are expired || 药物~. The medicine has lost its effectiveness 
Wirksamkeit Wirksamkeit verlieren 
efficacia perdere efficacia 
efficacité perdre de l'efficacité 
eficacia perder la eficacia effect, result 83 成效 [-] chéngxiào (achieved-result) effect, result: 取得~ get results || 有/没有~ be effective/not effective || 显著的remarkable results ' 证件~ credentials are expired || 药物~. The medicine has lost its effectiveness 17 失效 [-] shīxiào (lose-function) lose efficacy, loose effectiveness: 证件~ credentials are expired || 药物~. The medicine has lost its effectiveness '
Các nhà khoa học đã chứng minh hiệu quả của loại thuốc này. 
The scientists proved the effectiveness of this medicine.
Die Wissenschaftler bewiesen die Wirksamkeit dieser Medizin.
นักวิทยาศาสตร์ได้พิสูจน์ประสิทธิภาพของยานี้
科学家们证明了这种药物的有效性。